Mean PAP Equation:
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Mean Pulmonary Artery Pressure (mPAP) is the average pressure in the pulmonary artery during the cardiac cycle. It's a key hemodynamic measurement used to diagnose and monitor pulmonary hypertension.
The calculator uses the standard mPAP equation:
Where:
Explanation: The equation calculates the weighted average pressure, giving more importance to diastolic pressure which lasts longer in the cardiac cycle.
Details: Normal mPAP is 8-20 mmHg at rest. Values ≥25 mmHg at rest define pulmonary hypertension, while 21-24 mmHg may indicate early disease.
Tips: Enter both diastolic and systolic PAP values in mmHg. Systolic should be ≥ diastolic. Values are typically obtained from right heart catheterization.
Q1: Why is mPAP important?
A: mPAP is the primary hemodynamic parameter for diagnosing and classifying pulmonary hypertension severity.
Q2: How does this differ from systemic MAP?
A: Systemic MAP uses 1/3 of pulse pressure while pulmonary MAP traditionally uses 40% (though 1/3 is commonly used for simplicity).
Q3: When is right heart catheterization needed?
A: When non-invasive tests suggest pulmonary hypertension or for monitoring treatment response in known cases.
Q4: Are there alternative calculation methods?
A: Some use mPAP = 0.61×sPAP + 2 mmHg, but the standard formula is most widely accepted.
Q5: What factors can affect mPAP?
A: Exercise, hypoxia, lung disease, left heart disease, and pulmonary vascular disease all influence mPAP.